Literature analyzed to build SpliceAid database


PubMed ID



Authors (Year)



Title


Journal

1628625
Kiledjian M, Dreyfuss G. (1992)Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. EMBO J. 11(7):2655-64.
2533575
Garcia-Blanco MA, Jamison SF, Sharp PA. (1989)Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns.Genes Dev. 3(12A):1874-1886.
3386636
Swanson MS, Dreyfuss G. (1988)Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities. Mol Cell Biol. 8(5):2237-2241.
7510636
Burd CG, Dreyfuss G. (1994)RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing. EMBO J. 13(5): 1197-1204.
7512260
Matunis MJ, Xing J, Dreyfuss G. (1994)The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. Nucleic Acids Res. 22(6): 1059-67.
7543047
Tacke R, Manley JL. (1995)The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities. EMBO J. 14(14): 3540-3551.
7585247
Myer VE, Steitz JA. (1995)Isolation and characterization of a novel, low abundance hnRNP protein: A0. RNA. 1(2): 171-182.
7607214
Leffers H, Dejgaard K, Celis JE. (1995)Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains. Eur J Biochem. 230(2): 447-453.
7651409
Ramchatesingh J, Zahler AM, Neugebauer KM, Roth MB, Cooper TA. (1995)A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. Mol Cell Biol. 15(9):4898-4907.
7673195
Kajita Y, Nakayama J, Aizawa M, Ishikawa F. (1995)The UUAG-specific RNA binding protein, heterogeneous nuclear ribonucleoprotein D0. Common modular structure and binding properties of the 2xRBD-Gly family. J Biol Chem. 270(38): 22167-22175.
7688265
Siomi H, Siomi MC, Nussbaum RL, Dreyfuss G. (1993)The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein.Cell. 74(2):291-298.
7972035
Gao FB, Carson CC, Levine T, Keene JD. (1994)Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1. Proc Natl Acad Sci U S A. 91(23):11207-11211.
8083209
Gorlach M, Burd CG, Dreyfuss G. (1994)The determinants of RNA-binding specificity of the heterogeneous nuclear ribonucleoprotein C proteins. J Biol Chem. 269(37): 23074-8.
8174554
Fackelmayer FO, Dahm K, Renz A, Ramsperger U, Richter A. (1994)Nucleic-acid-binding properties of hnRNP-U/SAF-A, a nuclear-matrix protein which binds DNA and RNA in vivo and in vitro. Eur J Biochem. 221(2):749-757.
8321232
Ishikawa F, Matunis MJ, Dreyfuss G, Cech TR. (1993)Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n. Mol Cell Biol. 13(7): 4301-4310.
8449401
Patton JG, Porro EB, Galceran J, Tempst P, Nadal-Ginard B. (1993)Cloning and characterization of PSF, a novel pre-mRNA splicing factor. Genes Dev. 7(3):393-406.
8473331
Hamilton BJ, Nagy E, Malter JS, Arrick BA, Rigby WF. (1993)Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences. J Biol Chem. 268(12): 8881-7.
8497264
Levine TD, Gao F, King PH, Andrews LG, Keene JD. (1993)Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.Mol Cell Biol. 13(6):3494-3504.
8558240
Buckanovich RJ, Yang YY, Darnell RB. (1996)The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies. J Neurosci. 16(3):1114-1122.
8576255
Dember LM, Kim ND, Liu KQ, Anderson P. (1996)Individual RNA recognition motifs of TIA-1 and TIAR have different RNA binding specificities.J Biol Chem. 271(5):2783-2788.
8626503
Ma WJ, Cheng S, Campbell C, Wright A, Furneaux H. (1996)Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J Biol Chem. 271(14):8144-8151.
8626712
Chung S, Jiang L, Cheng S, Furneaux H. (1996)Purification and properties of HuD, a neuronal RNA-binding protein. J Biol Chem. 271(19):11518-11524.
8647811
DeMaria CT, Brewer G. (1996)AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradation. J Biol Chem. 271(21): 12179-84.
8789448
Timchenko LT, Timchenko NA, Caskey CT, Roberts R. (1996)Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy.Hum Mol Genet. 5(1):115-121.
8798770
Temsamani J, Pederson T. (1996)The C-group heterogeneous nuclear ribonucleoprotein proteins bind to the 5' stem-loop of the U2 small nuclear ribonucleoprotein particle. J Biol Chem. 271(40): 24922-24926.
8912635
Bhagavati S, Ghatpande A, Leung B. (1996)Identification of two nuclear proteins which bind to RNA CUG repeats: significance for myotonic dystrophy.Biochem Biophys Res Commun. 228(1):55-62.
8917439
Dejgaard K, Leffers H. (1996)Characterisation of the nucleic-acid-binding activity of KH domains. Different properties of different domains.Eur J Biochem. 241(2):425-431.
8948631
Timchenko LT, Miller JW, Timchenko NA, DeVore DR, Datar KV, Lin L, Roberts R, Caskey CT, Swanson MS. (1996)Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy. Nucleic Acids Res. 24(22): 4407-4414.
9037021
Tacke R, Chen Y, Manley JL. (1997)Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer. Proc Natl Acad Sci U S A. 94(4): 1148-1153.
9045688
Chung S, Eckrich M, Perrone-Bizzozero N, Kohn DT, Furneaux H. (1997)The Elav-like proteins bind to a conserved regulatory element in the 3'-untranslated region of GAP-43 mRNA.J Biol Chem. 272(10):6593-6598.
9121425
Chabot B, Blanchette M, Lapierre I, La Branche H. (1997)An intron element modulating 5' splice site selection in the hnRNP A1 pre-mRNA interacts with hnRNP A1. Mol Cell Biol. 17(4):1776-1786.
9122208
Holcik M, Liebhaber SA. (1997)Four highly stable eukaryotic mRNAs assemble 3' untranslated region RNA-protein complexes sharing cis and trans components.Proc Natl Acad Sci U S A. 94(6):2410-2414.
9130721
Gallego ME, Gattoni R, Stevenin J, Marie J, Expert-Bezancon A. (1997)The SR splicing factors ASF/SF2 and SC35 have antagonistic effects on intronic enhancer-dependent splicing of the beta-tropomyosin alternative exon 6A.EMBO J. 16(7):1772-1784.
9154818
Buckanovich RJ, Darnell RB. (1997)The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo. Mol Cell Biol. 17(6):3194-3201.
9155038
Myer VE, Fan XC, Steitz JA. (1997)Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay. EMBO J. 16(8):2130-2139.
9160751
Ostareck DH, Ostareck-Lederer A, Wilm M, Thiele BJ, Mann M, Hentze MW. (1997)mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.Cell. 16;89(4):597-606.
9182766
Berglund JA, Chua K, Abovich N, Reed R, Rosbash M. (1997)The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC. Cell. 89(5):781-787.
9214659
Perez I, Lin CH, McAfee JG, Patton JG. (1997)Mutation of PTB binding sites causes misregulation of alternative 3' splice site selection in vivo. RNA. 3(7): 764-778.
9234723
Chan RC, Black DL. (1997)The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream. Mol Cell Biol. 17(8):4667-4676.
9261396
Tsuchihara K, Tanaka T, Hijikata M, Kuge S, Toyoda H, Nomoto A, Yamamoto N, Shimotohno K. (1997)Specific interaction of polypyrimidine tract-binding protein with the extreme 3'-terminal structure of the hepatitis C virus genome, the 3'X.J Virol. 71(9):6720-6726
9275159
Li HP, Zhang X, Duncan R, Comai L, Lai MM. (1997)Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription-regulatory region of mouse hepatitis virus RNA. Proc Natl Acad Sci U S A. 94(18): 9544-9549.
9292499
Ashiya M, Grabowski PJ. (1997)A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart.RNA. 3(9):996-1015.
9341174
Lin Q, Taylor SJ, Shalloway D. (1997)Specificity and determinants of Sam68 RNA binding. Implications for the biological function of K homology domains. J Biol Chem. 272(43):27274-27280.
9353343
Hamilton BJ, Burns CM, Nichols RC, Rigby WF. (1997)Modulation of AUUUA response element binding by heterogeneous nuclear ribonucleoprotein A1 in human T lymphocytes. The roles of cytoplasmic location, transcription, and phosphorylation.J Biol Chem. 272(45):28732-28741.
9393875
Sokolowski M, Zhao C, Tan W, Schwartz S. (1997)AU-rich mRNA instability elements on human papillomavirus type 1 late mRNAs and c-fos mRNAs interact with the same cellular factors. Oncogene. 15(19):2303-2319.
9436904
Nagel RJ, Lancaster AM, Zahler AM. (1998)Specific binding of an exonic splicing enhancer by the pre-mRNA splicing factor SRp55. RNA. 4(1):11-23.
9436911
Gooding C, Roberts GC, Smith CW. (1998)Role of an inhibitory pyrimidine element and polypyrimidine tract binding protein in repression of a regulated alpha-tropomyosin exon. RNA. 4(1): 85-100.
9512519
Berglund JA, Abovich N, Rosbash M. (1998)A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition. Genes Dev. 12(6):858-867.
9546399
Tacke R, Tohyama M, Ogawa S, Manley JL. (1998)Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing. Cell. 93(1): 139-148.
9649504
Liu HX, Zhang M, Krainer AR. (1998)Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins. Genes Dev. 12(13): 1998-2012.
9649627
Soltaninassab SR, McAfee JG, Shahied-Milam L, LeStourgeon WM. (1998)Oligonucleotide binding specificities of the hnRNP C protein tetramer. Nucleic Acids Res. 26(14): 3410-3417.
9685407
Joseph B, Orlian M, Furneaux H. (1998)p21(waf1) mRNA contains a conserved element in its 3'-untranslated region that is bound by the Elav-like mRNA-stabilizing proteins.J Biol Chem. 273(32):20511-20516.
9710581
Lou H, Neugebauer KM, Gagel RF, Berget SM. (1998)Regulation of alternative polyadenylation by U1 snRNPs and SRp20. Mol Cell Biol. 18(9): 4977-85.
9740129
Mayeda A, Munroe SH, Xu RM, Krainer AR. (1998)Distinct functions of the closely related tandem RNA-recognition motifs of hnRNP A1.RNA. 4(9):1111-1123.
9765391
Gupta AK, Drazba JA, Banerjee AK. (1998)Specific interaction of heterogeneous nuclear ribonucleoprotein particle U with the leader RNA sequence of vesicular stomatitis virus. J Virol. 72(11):8532-8540.
9789075
Yang YY, Yin GL, Darnell RB. (1998)The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. Proc Natl Acad Sci U S A. 95(22):13254-13259.
9826658
Zheng ZM, Huynen M, Baker CC. (1998)A pyrimidine-rich exonic splicing suppressor binds multiple RNA splicing factors and inhibits spliceosome assembly.Proc Natl Acad Sci U S A. 95(24):14088-14093.
9848651
Dye BT, Buvoli M, Mayer SA, Lin CH, Patton JG. (1998)Enhancer elements activate the weak 3' splice site of alpha-tropomyosin exon 2. RNA. 4(12): 1523-1536.
9858533
Lou H, Helfman DM, Gagel RF, Berget SM. (1999)Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3'-terminal exon. Mol Cell Biol. 19(1):78-85.
9858549
Del Gatto-Konczak F, Olive M, Gesnel MC, Breathnach R. (1999)hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer.Mol Cell Biol. 19(1):251-260.
9858550
Schaal TD, Maniatis T. (1999)Multiple distinct splicing enhancers in the protein-coding sequences of a constitutively spliced pre-mRNA. Mol Cell Biol. 19(1): 261-73.
9880507
Shih SC, Claffey KP. (1999)Regulation of human vascular endothelial growth factor mRNA stability in hypoxia by heterogeneous nuclear ribonucleoprotein L. J Biol Chem. 274(3): 1359-1365.
9882309
Sokolowski M, Furneaux H, Schwartz S. (1999)The inhibitory activity of the AU-rich RNA element in the human papillomavirus type 1 late 3' untranslated region correlates with its affinity for the elav-like HuR protein. J Virol. 73(2):1080-1091.
9925777
Najera I, Krieg M, Karn J. (1999)Synergistic stimulation of HIV-1 rev-dependent export of unspliced mRNA to the cytoplasm by hnRNP A1.J Mol Biol. 285(5):1951-1964.
10022858
Schaal TD, Maniatis T. (1999)Selection and characterization of pre-mRNA splicing enhancers: identification of novel SR protein-specific enhancer sequences. Mol Cell Biol. 19(3): 1705-1719.
10037806
Gontarek RR, Gutshall LL, Herold KM, Tsai J, Sathe GM, Mao J, Prescott C, Del Vecchio AM. (1999)hnRNP C and polypyrimidine tract-binding protein specifically interact with the pyrimidine-rich region within the 3'NTR of the HCV RNA genome.Nucleic Acids Res. 27(6):1457-1463.
10072387
Chen CD, Kobayashi R, Helfman DM. (1999)Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat beta-tropomyosin gene. Genes Dev. 13(5):593-606.
10075998
Maurer F, Tierney M, Medcalf RL. (1999)An AU-rich sequence in the 3'-UTR of plasminogen activator inhibitor type 2 (PAI-2) mRNA promotes PAI-2 mRNA decay and provides a binding site for nuclear HuR.Nucleic Acids Res. 27(7):1664-1673.
10094314
Cavaloc Y, Bourgeois CF, Kister L, Stevenin J. (1999)The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers. RNA. 5(3): 468-483.
10202157
Blanchette M, Chabot B. (1999)Modulation of exon skipping by high-affinity hnRNP A1-binding sites and by intron elements that repress splice site utilization. EMBO J. 18(7): 1939-1952.
10406810
Caputi M, Mayeda A, Krainer AR, Zahler AM. (1999)hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing. EMBO J. 18(14):4060-4067.
10523623
Bourgeois CF, Popielarz M, Hildwein G, Stevenin J. (1999)Identification of a bidirectional splicing enhancer: differential involvement of SR proteins in 5' or 3' splice site activation. Mol Cell Biol. 19(11):7347-7356.
10523673
Charroux B, Angelats C, Fasano L, Kerridge S, Vola C. (1999)The levels of the bancal product, a Drosophila homologue of vertebrate hnRNP K protein, affect cell proliferation and apoptosis in imaginal disc cells.Mol Cell Biol. 19(11):7846-7856.
10573156
Ansari SA, Safak M, Gallia GL, Sawaya BE, Amini S, Khalili K. (1999)Interaction of YB-1 with human immunodeficiency virus type 1 Tat and TAR RNA modulates viral promoter activity.J Gen Virol. 80 (Pt 10):2629-2638.
10629063
Liu HX, Chew SL, Cartegni L, Zhang MQ, Krainer AR. (2000)Exonic splicing enhancer motif recognized by human SC35 under splicing conditions. Mol Cell Biol. 20(3): 1063-1071.
10676814
Lewis HA, Musunuru K, Jensen KB, Edo C, Chen H, Darnell RB, Burley SK. (2000)Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome.Cell. 100(3):323-332.
10811881
Jensen KB, Musunuru K, Lewis HA, Burley SK, Darnell RB. (2000)The tetranucleotide UCAY directs the specific recognition of RNA by the nova K-homology 3 domain. Proc Natl Acad Sci U S A. 97(11): 5740-5745.
10848602
Park S, Myszka DG, Yu M, Littler SJ, Laird-Offringa IA. (2000)HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA.Mol Cell Biol. 20(13):4765-4772.
10856256
Conte MR, Grune T, Ghuman J, Kelly G, Ladas A, Matthews S, Curry S. (2000)Structure of tandem RNA recognition motifs from polypyrimidine tract binding protein reveals novel features of the RRM fold.EMBO J. 19(12):3132-3141.
10857750
Tsui S, Dai T, Roettger S, Schempp W, Salido EC, Yen PH. (2000)Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1. Genomics. 65(3):266-273.
10911989
Chou MY, Underwood JG, Nikolic J, Luu MH, Black DL. (2000)Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing. Mol Cell. 5(6):949-957.
10913178
Millard SS, Vidal A, Markus M, Koff A. (2000)A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.Mol Cell Biol. 20(16):5947-5959.
10913193
Derry JJ, Richard S, Valderrama Carvajal H, Ye X, Vasioukhin V, Cochrane AW, Chen T, Tyner AL. (2000)Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability. Mol Cell Biol. 20(16): 6114-6126.
10931943
Hofmann Y, Lorson CLL, Stamm S, Androphy EJ, Wirth B. (2000)Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2). Proc Natl Acad Sci U S A. 97(17): 9618-9623.
10934202
Fogel BL, McNally MT. (2000)A cellular protein, hnRNP H, binds to the negative regulator of splicing element from Rous sarcoma virus. J Biol Chem. 275(41):32371-32378.
11003644
Markovtsov V, Nikolic JM, Goldman JA, Turck CW, Chou MY, Black DL. (2000)Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein. Mol Cell Biol. 20(20):7463-7479.
11024030
Shan J, Moran-Jones K, Munro TP, Kidd GJ, Winzor DJ, Hoek KS, Smith R. (2000)Binding of an RNA trafficking response element to heterogeneous nuclear ribonucleoproteins A1 and A2. J Biol Chem. 275(49): 38286-38295.
11046149
Wan L, Dockendorff TC, Jongens TA, Dreyfuss G. (2000)Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein.Mol Cell Biol. 20(22):8536-8547.
11096110
Lejeune F, Cavaloc Y, Stevenin J. (2001)Alternative splicing of intron 3 of the serine/arginine-rich protein 9G8 gene. Identification of flanking exonic splicing enhancers and involvement of 9G8 as a trans-acting factor.J Biol Chem. 276(11):7850-7858.
11098054
Lerga A, Hallier M, Delva L, Orvain C, Gallais I, Marie J, Moreau-Gachelin F. (2001)Identification of an RNA binding specificity for the potential splicing factor TLS. J Biol Chem. 276(9):6807-6816.
11106748
Forch P, Puig O, Kedersha N, Martinez C, Granneman S, Seraphin B, Anderson P, Valcarcel J. (2000)The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing. Mol Cell. 6(5): 1089-1098.
11172920
Sokolowski M, Schwartz S. (2001)Heterogeneous nuclear ribonucleoprotein C binds exclusively to the functionally important UUUUU-motifs in the human papillomavirus type-1 AU-rich inhibitory element. Virus Res. 73(2):163-175
11278454
Chung H , Derse D. (2001)Binding sites for Rev and ASF/SF2 map to a 55-nucleotide purine-rich exonic element in equine infectious anemia virus RNA. J Biol Chem. 276 (22): 18960-18967.
11278705
Thisted T, Lyakhov DL, Liebhaber SA. (2001)Optimized RNA targets of two closely related triple KH domain proteins, heterogeneous nuclear ribonucleoprotein K and alphaCP-2KL, suggest Distinct modes of RNA recognition.J Biol Chem. 276(20):17484-17496.
11285240
Buratti E, Dork T, Zuccato E, Pagani F, Romano M, Baralle FE. (2001)Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. EMBO J. 20(7):1774-1784.
11336712
Huang Y, Steitz JA. (2001)Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA.Mol Cell. 7(4):899-905.
11421362
Hastings ML, Wilson CM, Munroe SH. (2001)A purine-rich intronic element enhances alternative splicing of thyroid hormone receptor mRNA.RNA. 7(6):859-874.
11438677
Peled-Zehavi H, Berglund JA, Rosbash M, Frankel AD. (2001)Recognition of RNA branch point sequences by the KH domain of splicing factor 1 (mammalian branch point binding protein) in a splicing factor complex. Mol Cell Biol. 21(15):5232-5241.
11447123
Stickeler E, Fraser SD, Honig A, Chen AL, Berget SM, Cooper TA. (2001)The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. EMBO J. 20(14):3821-3830.
11470789
Buratti E, Baralle FE. (2001)Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9.J Biol Chem. 276(39):36337-36343.
11514570
Wilson GM, Sutphen K, Moutafis M, Sinha S, Brewer G. (2001)Structural remodeling of an A + U-rich RNA element by cation or AUF1 binding.J Biol Chem. 276(42):38400-38409.
11526107
Jacquenet S, Mereau A, Bilodeau PS, Damier L, Stoltzfus CM, Branlant C. (2001)A second exon splicing silencer within human immunodeficiency virus type 1 tat exon 2 represses splicing of Tat mRNA and binds protein hnRNP H. J Biol Chem. 276(44): 40464-75.
11532944
Schaeffer C, Bardoni B, Mandel JL, Ehresmann B, Ehresmann C, Moine H. (2001)The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif. EMBO J. 20(17): 4803-4813.
11571276
Caputi M, Zahler AM. (2001)Determination of the RNA Binding Specificity of the Heterogeneous Nuclear Ribonucleoprotein (hnRNP) H/H'/F/2H9 Family. J Biol Chem. 276(47): 43850-43859.
11575921
Tange TO, Kjems J. (2001)SF2/ASF binds to a splicing enhancer in the third HIV-1 tat exon and stimulates U2AF binding independently of the RS domain.J Mol Biol. 312(4):649-662.
11598017
Tange TO, Damgaard CK, Guth S, Valcarcel J, Kjems J. (2001)The hnRNP A1 protein regulates HIV-1 tat splicing via a novel intron silencer element. EMBO J. 20(20):5748-5758.
11602610
Raghavan A, Robison RL, McNabb J, Miller CR, Williams DA, Bohjanen PR. (2001)HuA and tristetraprolin are induced following T cell activation and display distinct but overlapping RNA binding specificities.J Biol Chem. 276(51):47958-47965.
11691992
Liu Z, Luyten I, Bottomley MJ, Messias AC, Houngninou-Molango S, Sprangers R, Zanier K, Kramer A, Sattler M. (2001)Structural basis for recognition of the intron branch site RNA by splicing factor 1.Science. 294(5544):1098-1102.
11719186
Chen CY, Gherzi R, Ong SE, Chan EL, Raijmakers R, Pruijn GJ, Stoecklin G, Moroni C, Mann M, Karin M. (2001)AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.Cell. 107(4):451-464.
11719189
Darnell JC, Jensen KB, Jin P, Brown V, Warren ST, Darnell RB. (2001)Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell. 107(4): 489-499.
11751603
Smith PJ, Spurrell EL, Coakley J, Hinds CJ, Ross RJ, Krainer AR, Chew SL. (2002)An exonic splicing enhancer in human IGF-I pre-mRNA mediates recognition of alternative exon 5 by the serine-arginine protein splicing factor-2/alternative splicing factor. Endocrinology. 143(1):146-154.
11753385
Perrotti D, Cesi V, Trotta R, Guerzoni C, Santilli G, Campbell K, Iervolino A, Condorelli F, Gambacorti-Passerini C, Caligiuri MA, Calabretta B. (2002)BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2.Nat Genet. 30(1):48-58.
11779509
Zhu J, Mayeda A, Krainer AR. (2001)Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins. Mol Cell. 8(6): 1351-1361.
11788707
Yuan X, Davydova N, Conte MR, Curry S, Matthews S. (2002)Chemical shift mapping of RNA interactions with the polypyrimidine tract binding protein.Nucleic Acids Res. 30(2):456-462.
11847131
Caputi M, Zahler AM. (2002)SR proteins and hnRNP H regulate the splicing of the HIV-1 tev-specific exon 6D. EMBO J. 21(4): 845-855.
11856759
Lapucci A, Donnini M, Papucci L, Witort E, Tempestini A, Bevilacqua A, Nicolin A, Brewer G, Schiavone N, Capaccioli S. (2002)AUF1 Is a bcl-2 A+U-rich element-binding protein involved in bcl-2 mRNA destabilization during apoptosis.J Biol Chem. 277(18):16139-16146.
11867641
Expert-Bezancon A, Le Caer JP, Marie J. (2002)Heterogeneous nuclear ribonucleoprotein (hnRNP) K is a component of an intronic splicing enhancer complex that activates the splicing of the alternative exon 6A from chicken beta-tropomyosin pre-mRNA.J Biol Chem. 277(19):16614-16623.
11925564
Cartegni L, Krainer AR. (2002)Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1. Nat Genet. 30(4):377-384.
11931771
Charlet-B N, Logan P, Singh G, Cooper TA. (2002)Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing. Mol Cell. 9(3):649-658.
12011088
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17702765
Yuan Y, Compton SA, Sobczak K, Stenberg MG, Thornton CA, Griffith JD, Swanson MS. (2007)Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs. Nucleic Acids Res. 35(16): 5474-5486.
17764653
Rho J, Choi S, Jung CR, Im DS. (2007)Arginine methylation of Sam68 and SLM proteins negatively regulates their poly(U) RNA binding activity. Arch Biochem Biophys. 466(1):49-57.
17869320
Zhao X, Fay J, Lambkin H, Schwartz S. (2007)Identification of a 17-nucleotide splicing enhancer in HPV-16 L1 that counteracts the effect of multiple hnRNP A1-binding splicing silencers.Virology. 369(2):351-363.
17908789
Winzen R, Thakur BK, Dittrich-Breiholz O, Shah M, Redich N, Dhamija S, Kracht M, Holtmann H. (2007)Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets.Mol Cell Biol. 27(23):8388-8400.
17913700
Novoyatleva T, Heinrich B, Tang Y, Benderska N, Butchbach ME, Lorson CL, Lorson MA, Ben-Dov C, Fehlbaum P, Bracco L, Burghes AH, Bollen M, Stamm S.(2008)Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing.Hum Mol Genet. 17(1):52-70.
17925491
Eiring AM, Neviani P, Santhanam R, Oaks JJ, Chang JS, Notari M, Willis W, Gambacorti-Passerini C, Volinia S, Marcucci G, Caligiuri MA, Leone GW, Perrotti D. (2008)Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis.Blood. 111(2):816-828.
17928403
Lee PT, Liao PC, Chang WC, Tseng JT. (2007)Epidermal growth factor increases the interaction between nucleolin and heterogeneous nuclear ribonucleoprotein K/poly(C) binding protein 1 complex to regulate the gastrin mRNA turnover.Mol Biol Cell. 18(12):5004-5013.
17942744
Warf MB, Berglund JA. (2007)MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T. RNA. 13(12): 2238-2251.
17950949
Cheunim T, Zhang J, Milligan SG, McPhillips MG, Graham SV. (2008)The alternative splicing factor hnRNP A1 is up-regulated during virus-infected epithelial cell differentiation and binds the human papillomavirus type 16 late regulatory element.Virus Res. 131(2):189-198.
17965020
Buxade M, Morrice N, Krebs DL, Proud CG. (2008)The PSF.p54nrb complex is a novel Mnk substrate that binds the mRNA for tumor necrosis factor alpha.J Biol Chem. 283(1):57-65.
18039683
Mori D, Sasagawa N, Kino Y, Ishiura S. (2008)Quantitative analysis of CUG-BP1 binding to RNA repeats.J Biochem. 143(3):377-383.
18075498
Fraser DJ, Phillips AO, Zhang X, van Roeyen CR, Muehlenberg P, En-Nia A, Mertens PR. (2008)Y-box protein-1 controls transforming growth factor-beta1 translation in proximal tubular cells.Kidney Int. 73(6):724-732.
18272582
Exline CM, Feng Z, Stoltzfus CM. (2008)Negative and positive mRNA splicing elements act competitively to regulate human immunodeficiency virus type 1 vif gene expression. J Virol. 82(8): 3921-3931.
18315555
Tardos JG, Eisenreich A, Deikus G, Bechhofer DH, Chandradas S, Zafar U, Rauch U, Bogdanov VY. (2008)SR proteins ASF/SF2 and SRp55 participate in tissue factor biosynthesis in human monocytic cells.J Thromb Haemost. 6(5):877-884.
18371932
Hua Y, Vickers TA, Okunola HL, Bennett CF, Krainer AR. (2008)Antisense masking of an hnRNP A1/A2 intronic splicing silencer corrects SMN2 splicing in transgenic mice.Am J Hum Genet. 82(4):834-848.
18391021
Goina E, Skoko N, Pagani F. (2008)Binding of DAZAP1 and hnRNPA1/A2 to an exonic splicing silencer in a natural BRCA1 exon 18 mutant.Mol Cell Biol. 28(11):3850-3860.
18463097
Izquierdo JM. (2008)Hu antigen R (HuR) functions as an alternative pre-mRNA splicing regulator of Fas apoptosis-promoting receptor on exon definition.J Biol Chem. 283(27):19077-19084.
18503770
Skoko N, Baralle M, Buratti E, Baralle FE. (2008)The pathological splicing mutation c.6792C>G in NF1 exon 37 causes a change of tenancy between antagonistic splicing factors. FEBS Lett. 582(15):2231-2236.
18534987
Cloutier P, Toutant J, Shkreta L, Goekjian S, Revil T, Chabot B. (2008)Antagonistic effects of the SRp30c protein and cryptic 5' splice sites on the alternative splicing of the apoptotic regulator Bcl-x. J Biol Chem. 283(31):21315-21324.
18573872
Zhou HL, Lou H. (2008)Repression of prespliceosome complex formation at two distinct steps by Fox-1/Fox-2 proteins. Mol Cell Biol. 28(17): 5507-5516.
18583400
Nechama M, Ben-Dov IZ, Briata P, Gherzi R, Naveh-Many T. (2008)The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels.FASEB J. 22(10):3458-3468.
18597733
Baralle M, Pastor T, Bussani E, Pagani F. (2008)Influence of Friedreich ataxia GAA noncoding repeat expansions on pre-mRNA processing. Am J Hum Genet. 83(1): 77-88.
18644987
Scott GK, Marx C, Berger CE, Saunders LR, Verdin E, Schafer S, Jung M, Benz CC. (2008)Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6.Mol Cancer Res. 6(7):1250-1258.
18650551
Palanisamy V, Park NJ, Wang J, Wong DT. (2008)AUF1 and HuR proteins stabilize interleukin-8 mRNA in human saliva.J Dent Res. 87(8):772-776.
18653529
Didiot MC, Tian Z, Schaeffer C, Subramanian M, Mandel JL, Moine H. (2008)The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer. Nucleic Acids Res. 36(15): 4902-4912.
18663000
Zhou A, Ou AC, Cho A, Benz EJ Jr, Huang SC. (2008)Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection. Mol Cell Biol. 28(19): 5924-5936.
18684992
Garcia-Mayoral MF, Diaz-Moreno I, Hollingworth D, Ramos A. (2008)The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets.Nucleic Acids Res. 36(16):5290-5296.
18719244
Topp JD, Jackson J, Melton AA, Lynch KW. (2008)A cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repressor of CD45 variable exon 4. RNA. 14(10): 2038-2049.
18776329
Takahama K, Kino K, Arai S, Kurokawa R, Oyoshi T. (2008)Identification of RNA binding specificity for the TET-family proteins.Nucleic Acids Symp Ser (Oxf). (52):213-214.
18794844
Feng Y, Chen M, Manley JL. (2008)Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator. Nat Struct Mol Biol. 15(10):1040-1048.
18806275
Masuda A, Shen XM, Ito M, Matsuura T, Engel AG, Ohno K. (2008)hnRNP H enhances skipping of a nonfunctional exon P3A in CHRNA1 and a mutation disrupting its binding causes congenital myasthenic syndrome. Hum Mol Genet. 17(24):4022-4035.
18929541
Zell R, Ihle Y, Effenberger M, Seitz S, Wutzler P, Gorlach M. (2008)Interaction of poly(rC)-binding protein 2 domains KH1 and KH3 with coxsackievirus RNA.Biochem Biophys Res Commun. 377(2):500-503.
19016857
Raponi M, Buratti E, Llorian M, Stuani C, Smith CW, Baralle D. (2008)Polypyrimidine tract binding protein regulates lternative splicing of an aberrant pseudoexon in NF1. FEBS J. 275(24): 6101-6108.
19111562
Goncalves V, Theisen P, Antunes O, Medeira A, Ramos JS, Jordan P, Isidro G. (2009)A missense mutation in the APC tumor suppressor gene disrupts an ASF/SF2 splicing enhancer motif and causes pathogenic skipping of exon 14. Mutat Res. 662(1-2): 33-36.
19124611
Rossbach O, Hung LH, Schreiner S, Grishina I, Heiner M, Hui J, Bindereif A. (2009)Auto- and cross-regulation of the hnRNP L proteins by alternative splicing. Mol Cell Biol. 29(6): 1442-1451.
19147685
Bian Y, Masuda A, Matsuura T, Ito M, Okushin K, Engel AG, Ohno K. (2009)Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome. Hum Mol Genet. 18(7):1229-1237.
19298794
Lee DH, Lim MH, Youn DY, Jung SE, Ahn YS, Tsujimoto Y, Lee JH. (2009)hnRNP L binds to CA repeats in the 3'UTR of bcl-2 mRNA. Biochem Biophys Res Commun. 382(3): 583-587.
19304800
Loughlin FE, Mansfield RE, Vaz PM, McGrath AP, Setiyaputra S, Gamsjaeger R, Chen ES, Morris BJ, Guss JM, Mackay JP. (2009)The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences. Proc Natl Acad Sci U S A. 106(14): 5581-5586.
19339348
Choi EY, Pintel D. (2009)Splicing of the large intron present in the non-structural gene of minute virus of mice (MVM) is governed by TIA-1/TIAR binding downstream of the non-consensus donor. J Virol. 83(12):6306-6311
19404736
Millevoi S, Bernat S, Telly D, Fouque F, Gladieff L, Favre G, Vagner S, Toulas C. (2009)The c.5242C>A BRCA1 missense variant induces exon skipping by increasing splicing repressors binding. Breast Cancer Res Treat.
19458619
Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG. (2009)The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.Nature. 459(7249):1010-1014.
19561594
Ray D, Kazan H, Chan ET, Pena Castillo L, Chaudhry S, Talukder S, Blencowe BJ, Morris Q, Hughes TR. (2009)Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins.Nat Biotechnol. 27(7):667-670.
19564422
Tang ZZ, Zheng S, Nikolic J, Black DL. (2009)Developmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.Mol Cell Biol. 29(17):4757-4765.
19667073
Okunola HL, Krainer AR. (2009)Cooperative-binding and splicing-repressive properties of hnRNP A1.Mol Cell Biol. 29(20):5620-5631.
19843576
Chandradas S, Deikus G, Tardos JG, Bogdanov VY. (2010)Antagonistic roles of four SR proteins in the biosynthesis of alternatively spliced tissue factor transcripts in monocytic cells.J Leukoc Biol. 87(1):147-152.
19910374
Haque A, Buratti E, Baralle FE. (2010)Functional properties and evolutionary splicing constraints on a composite exonic regulatory element of splicing in CFTR exon 12.Nucleic Acids Res. 38(2):647-659.
19926721
Fisette JF, Toutant J, Dugre-Brisson S, Desgroseillers L, Chabot B. (2010)hnRNP A1 and hnRNP H can collaborate to modulate 5' splice site selection.RNA. 16(1):228-238.
19946215
Heiner M, Hui J, Schreiner S, Hung LH, Bindereif A. (2010)HnRNP L-mediated regulation of mammalian alternative splicing by interference with splice site recognition.RNA Biol. 7(1):56-64.
20100605
Russo A, Siciliano G, Catillo M, Giangrande C, Amoresano A, Pucci P, Pietropaolo C, Russo G. (2010)hnRNP H1 and intronic G runs in the splicing control of the human rpL3 gene.Biochim Biophys Acta. 1799(5-6):419-428.
20631008
Dujardin G, Buratti E, Charlet-Berguerand N, Martins de Araujo M, Mbopda A, Le Jossic-Corcos C, Pagani F, Ferec C, Corcos L. (2010)CELF proteins regulate CFTR pre-mRNA splicing: essential role of the divergent domain of ETR-3.Nucleic Acids Res. 38(20):7273-7285.

 

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